Abstract Background Understanding human genetic influences on the gut microbiota helps elucidate the mechanisms by which genetics may influence health outcomes.Typical microbiome genome-wide association studies (GWAS) marginally assess the association between individual genetic variants and individual microbial taxa.We propose a novel approach, the

At the end of the build-operate-transfer road concession period, an optimal model for the operation of public toll roads is created based on user heterogeneity regarding the values of time for different road users.The impact of user heterogeneity on operation costs for government and private firms is subsequently analyzed on the following critical

Summary: The differentiation of naive CD8+ T lymphocytes into cytotoxic effector and memory CTL results in large-scale changes in transcriptional and phenotypic profiles.Little is known about how large-scale changes in genome organization underpin these transcriptional programs.We use Hi-C to map changes in the spatial organization of long-range ge

Real-world degradations deviate from ideal degradations, as most deep learning-based scenarios involve the ideal synthesis of low-resolution (LR) counterpart images by popularly used bicubic interpolation.Moreover, supervised learning approaches rely on many high-resolution (HR) and LR image wahl power grip clippers pairings to reconstruct missing